Protection from neuropathy in extreme duration type 1 diabetes
نویسندگان
چکیده
منابع مشابه
Protection From Retinopathy and Other Complications in Patients With Type 1 Diabetes of Extreme Duration
OBJECTIVE To assess complication prevalence and identify protective factors in patients with diabetes duration of ≥50 years. Characterization of a complication-free subgroup in this cohort would suggest that some individuals are protected from diabetes complications and allow identification of endogenous protective factors. RESEARCH DESIGN AND METHODS Cross-sectional, observational study of 3...
متن کاملCharacterization of Circulating and Endothelial Progenitor Cells in Patients With Extreme-Duration Type 1 Diabetes
OBJECTIVE We characterized and correlated endothelial progenitor cells (EPCs) and circulating progenitor cells (CPCs) with lack of vascular complications in the Joslin Medalist Study in patients with type 1 diabetes for 50 years or longer. RESEARCH DESIGN AND METHODS EPC and CPC levels were ascertained by flow cytometry and compared among Medalists (n = 172) with or without diabetic retinopat...
متن کاملMANUSCRIPT TITLE Auditory Neuropathy in Individuals with Type 1 Diabetes RUNNING TITLE Auditory Neuropathy in Type 1 Diabetes
Gary Rance: Responsible for study design, management, data analysis and manuscript preparation. Structured Abstract Peripheral neuropathy is a major consequence of diabetes mellitus with up to 50% of patients showing clinically significant neural injury during the disease course. Hearing loss (as defined by impaired sound detection thresholds) is a recognized symptom of DM, but the possibility ...
متن کاملPulse pressure and cardiovascular autonomic neuropathy according to duration of type 1 diabetes.
BACKGROUND To evaluate changes in pulse pressure (PP) and markers of cardiovascular autonomic neuropathy (CAN) according to duration of type 1 diabetes mellitus (T1DM). METHODS This cross-sectional controlled study evaluated 159 diabetic patients during a 3-min posture test (standing-squatting-standing) with continuous measurement of systolic (SBP), diastolic (DBP) and mean (MBP) blood pressu...
متن کاملMedalists with extreme duration of type 1 diabetes exhibit only mild diastolic dysfunction and myocardial fibrosis.
Medalists are a unique subset of patients with more than 50 years of type 1 diabetes. One would expect these patients to have significant microvascular and macrovascular complications. However, the Joslin observational study showed that of their medalists, a substantial proportion remained free of proliferative diabetic retinopathy (42.6%), nephropathy (86.9%), and neuropathy (39.4%) (1). Wheth...
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ژورنال
عنوان ژورنال: Journal of the Peripheral Nervous System
سال: 2020
ISSN: 1085-9489,1529-8027
DOI: 10.1111/jns.12423